Glycosyl bis-porphyrin conjugates: synthesis and potential application in PDT.
نویسندگان
چکیده
Syntheses of new glycosylated neutral and cationic porphyrin dimers linked at the meso-position via a flexible hydrocarbon chain are described. A detailed 1H and 13C NMR study allows their complete structural elucidation. The UV-visible, fluorescence and MALDI mass spectra are also presented. Photocytotoxicities of these compounds against K562 leukaemia cell line are compared to those of Photofrin II.
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ورودعنوان ژورنال:
- Bioorganic & medicinal chemistry
دوره 14 23 شماره
صفحات -
تاریخ انتشار 2006